INDUCIBLE CRISPR ACTIVATION SCREEN FOR INTERFERON-STIMULATED GENES IDENTIFIES OAS1 AS A SARS-COV-2 RESTRICTION FACTOR.

Inducible CRISPR activation screen for interferon-stimulated genes identifies OAS1 as a SARS-CoV-2 restriction factor.

Interferons establish an antiviral state through the induction of hundreds of interferon-stimulated genes (ISGs).The mechanisms and viral specificities for most ISGs remain incompletely understood.To enable high-throughput interrogation of ISG antiviral functions in pooled genetic screens while mitigating potentially confounding KARAMBIT effects of

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Evaluation of Continuous Lactate Monitoring Systems within a Heparinized In Vivo Porcine Model Intravenously and Subcutaneously

We present an animal model used to evaluate Course a pied - Femme - Vetements - Collant - Lamine the in vivo performance of electrochemical amperometric continuous lactate sensors compared to blood gas instruments.Electrochemical lactate sensors were fabricated, placed into 5 Fr central venous catheters (CVCs), and paired with wireless potentiostat

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Development of the Homeless Health Access to Care Tool to identify health-related vulnerability among people experiencing homelessness: Delphi study, Australia

Objectives In this paper, we report the development of the Homeless Health Access to Care Tool.This tool aims to improve the gap in assessing health need and capacity to access healthcare of people experiencing homelessness.Tools exist that prioritise people experiencing homelessness for housing, but none specifically designed to prioritise for hea

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Review: Walburga Freitag (2005). Contergan. Eine genealogische Studie des Zusammenhangs wissenschaftlicher Diskurse und biographischer Erfahrungen [Contergan. A Genealogical Study on Scientific Discourse and Biography]

In this genealogical study, Walburga FREITAG explores the conditions of subjectivity-building in relation to the powerful medical discourse on Contergan.The discourse theory of Michel FOUCAULT dominates the key words for the empirical research: discourse, knowledge, power and body.The study aims to describe a transformation process, starting as a "

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